Dance the Night Away at O’Brien’s Nightlife in Downtown Annapolis

December 18, 2025•1 min read

Looking for a lively place to spend your Friday and Saturday nights in Annapolis? O’Brien’s Oyster Bar & Seafood Tavern has you covered with O’Brien’s Nightlife, a weekly late-night dance party featuring live DJs and the biggest dance floor in Downtown Annapolis.

Weekend Nights, Live DJs, and Nonstop Energy

Every Friday and Saturday night from 10:00 PM to 1:45 AM, O’Brien’s transforms into one of the hottest nightlife spots in the city. With live DJs spinning crowd-favorite tracks and a high-energy atmosphere, it’s the perfect place to dance, unwind, and enjoy a night out with friends.

Whether you’re celebrating the weekend, meeting up after dinner, or just looking to enjoy great music and good vibes, O’Brien’s Nightlife delivers an unforgettable late-night experience.

Event Details

📍 Location:
O’Brien’s Oyster Bar & Seafood Tavern
113 Main St, Annapolis, MD 21401

🕙 Time:
10:00 PM – 1:45 AM

📅 When:
Every Friday & Saturday

💲 Admission:
Free to the public

📞 Contact:
(410) 268-6288
✉️ [email protected]

🌐 Website:
Visit O’Brien’s website for more details

Why O’Brien’s Nightlife?

Downtown Annapolis’ largest dance floor
Live DJs every weekend
No cover charge
Central location on Main Street
A go-to spot for locals and visitors alike

Bottom Line

If you’re looking for a fun, high-energy nightlife experience in Annapolis, O’Brien’s Nightlife is the place to be. Grab your friends, hit the dance floor, and make the most of your weekend—no tickets required.

Heather Taylor, GRI

I’m Heather Taylor, a Realtor® with RE/MAX One in Annapolis, Maryland, proudly serving buyers and sellers throughout Anne Arundel and Prince George’s Counties — including Annapolis, Crofton, Gambrills, Odenton, Davidsonville, Crownsville, Severn, Severna Park, Glen Burnie, Pasadena, Bowie, and beyond. Real estate is one of my greatest passions, and I dedicate the time, energy, and focus needed to ensure my clients always feel supported. My goal is to make every transaction as smooth and stress-free as possible while helping you achieve your real estate dreams. My clients know me for my calm, responsive guidance, deep local knowledge, and the personalized care I bring to every step of the process. Whether you’re relocating, downsizing, or making room to grow, I provide strategic, high-touch support tailored to your unique goals — never a one-size-fits-all approach. Relocation Downsizing with ease and confidence Upsizing and move-up strategies for growing families

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